Photo 1 of 4100 E Mississippi Ave 4th Floor, Denver, CO 80246
Photo 2 of 4100 E Mississippi Ave 4th Floor, Denver, CO 80246
Photo 3 of 4100 E Mississippi Ave 4th Floor, Denver, CO 80246

Regus Denver - East Mississippi Ave

4100 E Mississippi Ave 4th Floor, Denver, CO 80246

Position your business in the lively Glendale neighborhood with flexible workspace options at Regus. This modern granite-grey tower features a welcoming foyer, setting a professional tone for you and your guests. Choose from a selection of private offices, coworking areas, and meeting rooms equipped with videoconferencing and presentation technology, all easily managed through a convenient app.

Enjoy the comfort of thoughtfully designed breakout spaces and well-appointed kitchen areas for informal gatherings or a quick coffee. Situated close to Cherry Creek and Denver’s dynamic downtown, this location offers a strategic address with excellent access to local amenities and transport connections.

5 Reasons to choose this workspace:

Private Workspace
Services included
Flexible term
Fixed cost
Fast move in

Regus Denver - East Mississippi Ave Office Space for Rent

5 Spaces Available
Property Details
Property Type
Office
Last Updated
3/25/2026
Regus Denver - East Mississippi Ave location

Commute and network effortlessly with bus stops right outside the office doors and an easily accessible citywide rail network. Visiting clients enjoy a straightforward journey via the I-25, located less than 2km away, running north-south from Colorado’s capital, Denver. A variety of lunch options are nearby, with a diverse mix of restaurants and cafés just a short walk away, along with the Hyatt Place Denver/Cherry Creek next door. After work, downtown Denver offers an array of restaurants and a lively entertainment scene, including live music and theatre productions.

Transport & Infrastructure

Regus sits near major roadways, making commutes straightforward for those driving via I-25. Bus stops are positioned just outside the building, and the area connects easily to the city’s rail network. For travelers, Denver International Airport and Rocky Airport are both within driving distance. Local transit options support daily movement, while those visiting from out of town have hotel choices such as the Hyatt Place Denver/Cherry Creek nearby.

Dining & Hospitality

Several restaurants and cafés are within walking distance, including Mango Mango Dessert and Crave Mediterranean Grill. Lan’s Noodles & Dumplings offers additional lunch options close by. After work, downtown Denver features a mix of dining and entertainment venues. For those needing a serviced office, nearby hotels like the Hampton Inn & Suites Denver-Cherry Creek provide accommodation for clients or team members.

Gyms & Fitness

Planet Fitness is located a short distance from the building, making it easy to fit in a workout before or after office hours. Life Time also operates in the area, offering a range of fitness services. For those interested in a shared workspace, access to local gyms supports employee wellbeing. Infinity Park provides additional space for recreation and sports events.