Office Space for Rent San Fernando Valley - Central

Hamlin Street

14431 Hamlin Street

From $8,250/MO

Situated in the vibrant neighborhood of Van Nuys, the location offers an attractive blend of urban convenience and suburban tranquility. The nearby Woodley Park provides a serene natural escape for office or medical professionals, while also being just a short drive from the bustling retail and dining scene along Ventura Boulevard. Close proximity to major thoroughfares such as the 405 and 101 Freeways ensures easy accessibility for both clients and employees. Additionally, the property is surrounded by a variety of healthcare facilities, including the nearby Valley Presbyterian Hospital, making it an ideal location for medical practitioners seeking a centralized and dynamic setting.

Regus Encino - Ventura Blvd

16501 Ventura Blvd Suite 400

Coworking from $369/MO

Clearly visible on the corner of Hayvenhurst Avenue and Ventura Boulevard is this eye-catching business center. The building's immediate neighbors include many businesses specializing in law, as well as media, broadcasting and financial services. A key attraction is the business center's prominent location, close to many amenities, which makes it highly accessible.

Regus Sherman Oaks - Ventura Blvd

15233 Ventura Blvd Suite 500

Coworking from $309/MO

Situated in a distinctive and contemporary 13-storey office building, this business center is the perfect location for your new offices or particular workspace solutions or requirements. The centers offers fully furnished and equipped executive suites, private and shared offices and open-plan work spaces. All of these options are available on flexible terms and with customizable space, the center is able to cater for nearly every unique business requirement. With meeting rooms available when ever you need, and a business lounge which is perfect for relaxed team catch-ups, you have everything you need all in one place.

Premier Workspaces

14500 Roscoe Boulevard (PAN) 4th Floor

From $75/MO

This beautiful 14,500-square-foot business center is in a 6-story mid-rise building offering panoramic views. The workspace features 58 private windows and interior spaces for 1 to 3 people per office. The refined design and stunning landmark architecture are locally renowned as a commercially significant business establishment incorporating a neutral palette, international style, and industrial materials to create an elegant and fun workspace. Spacious, fully-furnished offices offer a team somewhere to work comfortably, where members can move in and get started - no need for time wasted setting up various desks.

Premier Workspaces

15260 Ventura Boulevard (SO1) Sherman Oaks - Valley Executive Tower, Suite 1200

From $95/MO

This vibrant, impressive, and technologically sophisticated class-A office building offers serviced office suites and a further range of workspace solution packages available for all types of business clients with flexible terms for obtaining immediate occupancy and the ability to expand or downsize your business on short notice, giving your business flexibility not available in traditional office space. Other amenities are also available, which include spacious meeting rooms, conferencing facilities, breakout space, management and support services via the dedicated teams of specialist staff, and more.

15904 Strathern St

From $940/MO

Gloria/Stathern

5535 Balboa Blvd

From $5,674/MO

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400 SAN FERNANDO MISSION BLVD

From $7,215/MO

Corner Property

Oriente Plaza

18350 Ventura Blvd

From $2,450/MO

Newly renovated building offering premium, move-in-ready office suites on a prime stretch of Ventura Blvd in Tarzana. Perfect for medical professionals, therapists, accountants, legal advisors, or creative agencies. Key Property Highlights: • Bright, open spaces featuring floor-to-ceiling windows facing Ventura Blvd. • Upgraded interiors with , modern hardwood-style flooring. • Maximum convenience: Exceptional 101 Freeway access and just minutes from Cedars-Sinai Providence Tarzana Medical Center. • Walkable layout close to premium local retail, dining, and coffee shops. Pricing is all-inclusive (includes utilities and parking) with rents starting from $1,950/month. Each suite features its own individual climate-controlled AC unit. Individual suites are ~600 to 750 sq. ft., with the option to combine adjacent units up to 1,800 sq. ft.

Sepulveda Blvd

5658 Sepulveda Blvd

From $1,254/MO

A great office building located in the heart of Sherman Oaks on Sepulveda Blvd. Short distance to 101 and 405 freeways, Ventura Blvd, Costco, Ace Hardware, Hampton Inn Suites, Target, WLA and much more. Building has ample parking and provides a large elevator for your convenience.

Law Office of Marielys Acosta

6263 Van Nuys Blvd

From $500/MO

Private office for rent within a private law firm. Furnished. Access to shared Conference Room. Private, separate bathroom. Access to shared kitchen. Private and gated parking in rear with electric gate remote.

Covello Creative Offices & Warehouse Hub

14141 Covello St

From $850/MO

Flexible, private offices in a secured gated warehouse facility in Van Nuys. Offices range from 100–165 sq ft, all with 24/7 access, high-speed Wi-Fi, shared kitchenette, bathrooms, and on-site warehouse support available for businesses needing fulfillment or storage. Month-to-month leases starting at $850. Ideal for e-commerce, creatives, or small businesses.

14435 Hamlin St

From $1,350/MO

Located close to the intersection of Van Nuys & Victory Blvd. Medical building with easy access to public transit and within walking distance to many area amenities. Close to Van Nuys Government Center Easy access to public transit. Signage

15000 Ventura Blvd

From $11,956/MO

Sherman Oaks

6345 Balboa Boulevard

6345 Balboa Blvd

From $2,283/MO