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Office Space for Rent Charleston

Venture X

4900 O’Hear Avenue Suites 100 & 200

3 Spaces, 1 - 40 ^ppl

Coworking from $399/MO

This business center provides companies with move-in ready, all-inclusive office space, allowing each business to focus on their tasks while being part of a larger community of professionals. Here, the space offers amenities including: Unlimited coffee, High-tech meeting rooms, café offering fresh food and an array of drink options, mail services, cleaning services and free parking. The building itself is accessible 24 hours a day, so is suitable for any kind of business hours! There is also an on-site admin support team who can assist with telephone answering and mail handling letting you focus on work.

537 Folly Road

1 Space, 1 - 17 ^ppl

(2,087^SF)

From $3,593/MO

Located in the heart of James Island, the area surrounding the property at 357 Folly Road offers a vibrant mix of historic charm and modern amenities. Just across from the Merchants Village with Publix as its anchor tenant and Melvins directly across the street, tenants will find convenient access to shopping and dining options. Additionally, the property is just a short distance away from the scenic Folly Beach and the stunning James Island County Park. This prime location provides office tenants with a perfect blend of work-friendly surroundings and easy access to leisure activities and essential amenities.

46 State St

1 Space, 1 - 12 ^ppl

(1,500^SF)

From $4,500/MO

Located in the heart of historic Downtown Charleston, 46 State Street, Unit B offers a rare opportunity to lease approximately 1,500 square feet of charming office or retail space in one of the city’s most desirable and walkable locations. Situated just off Queen Street and Cumberland, the property is surrounded by Charleston’s renowned restaurants, boutique retailers, hotels, galleries, and historic destinations, providing an exceptional setting for businesses looking to establish a presence in the heart of the Peninsula.

1219 Hobart Avenue

1 Space, 1 - 21 ^ppl

(2,600^SF)

From $4,333/MO

Located just off Highway 61 in the heart of West Ashley, 1219 Hobart Avenue offers convenient access to Charleston's major commercial corridors and surrounding residential neighborhoods. The property is in close proximity to U.S. Highway 17 and provides convenient connectivity to I-526, Downtown Charleston, North Charleston, and the greater Charleston region. Its central West Ashley location makes the property particularly well suited for a daycare, educational facility, professional office, or neighborhood service business seeking accessibility and a freestanding location.

Office for Lease

1524 Ashley River Road

1 Space, 1 - 10 ^ppl

(1,272^SF)

Discover the charm of the Ashley River Road neighborhood in Charleston, SC. Nestled amidst historic oak trees and surrounded by picturesque waterways, the area embodies the quintessential Lowcountry experience. Just minutes from the property, tenants can explore the scenic beauty of West Ashley Greenway's walking trails. Nearby shopping and dining options abound, with Charleston's iconic historic district and The Citadel also within easy reach. This vibrant area seamlessly blends Southern hospitality with modern amenities, making it an ideal location for your office or office building. Experience the best of Charleston's rich culture and thriving business community at this prime location.

172 Ashley Avenue

1 Space, 1 - 16 ^ppl

(1,978^SF)

From $6,181/MO

Located on MUSC's campus, adjacent to the Horseshoe. This is an opportunity for a Bank to lease a turn key office space complete with 14 parking space and a drive-thru. The previous tenant was in this location for 14 years. MUSC is the second largest employer in the Charleston SC Metro Area.

134 Meeting St

1 Space, 1 - 9 ^ppl

(1,109^SF)

Step into the vibrant energy of Charleston's historic district, just moments from the property. Explore the charming streets lined with boutique shops, cozy cafes, and top dining spots like Husk, The Darling Oyster Bar, and Fleet Landing. Immerse yourself in the city's rich history at nearby attractions such as Waterfront Park, the iconic Pineapple Fountain, and the bustling City Market. With its unique blend of Southern charm and modern amenities, the area offers a captivating mix of convenience and culture for office tenants. Enjoy easy access to public transportation and major highways, ensuring seamless connectivity and making the location an ideal choice for a dynamic and diverse business environment.

174 Meeting St

1 Space, 1 - 120 ^ppl

(15,039^SF)

Step into the bustling energy of Charleston's historic district, just a stone's throw from the property. Explore the charming streets lined with boutique shops, inviting cafes, and renowned dining destinations like Husk, The Darling Oyster Bar, and Fleet Landing, perfect for client meetings and team outings. Dive into the city's rich history at attractions such as Waterfront Park, the iconic Pineapple Fountain, and the vibrant City Market. With its unique blend of Southern charm and modern amenities, the area offers a captivating mix of convenience and culture for office tenants. Enjoy easy access to public transportation and major highways, ensuring seamless connectivity and making the location an ideal choice for a dynamic and diverse business environment.

Isabella Office

11 Isabella St Suite A

1 Space, 1 - 13 ^ppl

(1,650^SF)

From $3,987/MO

Located in the ''Upper Peninsula'' district in downtown Charleston, this area is in a current growth stage.

West Ashley Office Space for Lease

2090 Executive Hall Rd

1 Space, 1 - 7 ^ppl

(850^SF)

From $1,275/MO

Convenient location oﬀ of Savage Road. Quick access to Glenn McConnell Blvd, I-526 and Savannah Highway.

83 Mary Pop Up Bagel Co Tenancy

83 Mary St

3 Spaces, 1 - 12 ^ppl

(1,246 - 1,542^SF)

From $3,634/MO

This four-story building offers incredible versatility and Co Tenancy with the popular Pop-Up Bagel's first South Carolina Location: Second & Third Floors - Lease alongside the rooftop venue or use independently for retail, showroom, executive suites, creative office, or other purposes. Each floor features abundant natural light, high ceilings, and an open layout. 2nd floor 1,542 SF, 3rd Floor 1,532 SF Rooftop 1,246 SF Rooftop - A showstopper space with panoramic views, not subject to the late-night ordinance. Located in the heart of Charleston's most dynamic district, King Street is renowned for its shopping, dining, nightlife, and accommodations. Nearby neighbors include West Elm, Halls Chophouse, Macintosh, The Dewberry Hotel, Charleston Music Hall, Woolfe Street Playhouse, Music Farm, Benny's Pizza, Vintage, Prohibition, Callie's Hot Little Biscuit, and many more. A one-of-a-kind property for hospitality, retail, or creative ventures in Charleston's most sought-after corridor.

Medical Office Building-Redevelopment Opportunity

2125 Charlie Hall Blvd

1 Space, 1 - 105 ^ppl

(13,113^SF)

From $21,855/MO

Centrally located in West Ashley in the heart of the medical and retail district.

7 Radcliffe St Ste 301

1 Space, 1 - 22 ^ppl

(2,750^SF)

From $5,967/MO

*** SUBLEASING PRICE IS $5000 per month***** Enjoy this prime office space in the heart of Downtown Charleston! Tall ceilings, exposed brick and historic hardwood floors make this third floor suite stand out. Complete with a conference room, work space and an otherwise open floorplan. This space boasts a shared breakroom and freshly remodeled bathrooms. Multiple on site parking spaces are available at an additional cost! Listed as a sublet but also available as a relet opportunity! Sublet expires on 4/30/2027. Current rent is $26/sf, increasing to $26.78 on 5/1/25 and then $27.58/sf 5/1/26.

Scene on Meeting

394 Meeting St

2 Spaces, 1 - 30 ^ppl

(1,122 - 3,039^SF)

From $1,870/MO

Prominent location on Meeting St. adjacent to the Charleston School of Law. Surrounded by multi family, office and the world class restaurant and retail Charleston has to offer.