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Office Space for Rent Kissimmee

Poinciana Medical Office

1050 Cypress Parkway

1 Space, 1 - 48 ^ppl

(6,041^SF)

From $12,585/MO

Free-standing medical office building in the Poinciana Towne Center with increasing demand for medical and professional services

1821 Armstrong Blvd

1 Space, 1 - 144 ^ppl

(2,500^SF)

Now available: a brand-new medical building ideally located at US-192 and Armstrong in Kissimmee, Florida. Surrounded by thriving medical facilities and less than three miles from the hospital, this location offers unmatched accessibility for patients and providers alike. This is a rare opportunity to position your business in the heart of the rapidly expanding South Orlando medical market.

City Centre

111 E Monument Ave

3 Spaces, 1 - 35 ^ppl

(2,436 - 4,400^SF)

From $3,958/MO

Class A office space located in the heart of Historic Downtown Kissimmee. Footsteps to the SunRail Station, AMTRACK Train Station, Greyhound Bus Station, Kissimmee Civic Center, Hart Memorial Central Libary, and Kissimmee Lakefront Park. County Buildings .3 miles, Brinson Park .70 and Toho Marine .50 mile. BY APPOINTMENT ONLY WITH THE LISTING BROKER WITH 24-HOUR NOTICE.

198 Broadway Office

1 Space, 1 - 26 ^ppl

(3,275^SF)

From $8,596/MO

Located at the signalized corner of Broadway and Dakin Avenue, this property offers exceptional visibility and accessibility in the heart of historic downtown Kissimmee. Just minutes from the courthouse, SunRail and Amtrak stations, major hospitals, medical parks, and Lake Tohopekaliga. Surrounded by government offices, shops, and restaurants—ideal for professional, medical, or retail use.

1060 Cypress Pkwy # 104

1 Space, 1 - 34 ^ppl

(4,237^SF)

From $8,826/MO

1060 Cypress Parkway is a single-story professional and medical office building strategically situated within Osceola County’s rapidly expanding Poinciana submarket. Offering seamless regional connectivity, the property provides effortless access to I-4, SR 538, and SR 429, making it a highly accessible hub for patients and staff across Osceola, Polk, and Orange counties. The asset boasts high-visibility street frontage along a major commercial corridor with close proximity to HCA Poinciana with no HCA exclusivity restrictions.

4560 East Irlo Bronson Memorial Highway

6 Spaces, 1 - 9 ^ppl

(210 - 1,080^SF)

From $5,489/MO

New Construction Along Prime Tourist Corridor – Kissimmee, FL Now leasing brand-new retail and office suites at ICON 192, a modern mixed-use development located directly on US Highway 192, minutes from Walt Disney World and Orlando’s top tourist destinations. This high-traffic corridor offers unmatched exposure and access to both locals and tourists. Located in a fast-growing area with a mix of residential, tourist, and commercial demand, ICON 192 is perfect for businesses seeking a professional and high-exposure location.

319 W Oak St

1 Space, 1 - 24 ^ppl

(3,000^SF)

From $6,999/MO

Located in the downtown area of Kissimmee, just west of the city’s historic core. It benefits from convenient access to several major transportation routes, including US Highway 17/92/441 (Orange Blossom Trail), which runs north–south a short distance east of the site and serves as one of the primary arterial corridors through the area. The property is also near John Young Parkway, another key north–south roadway providing regional connectivity. To the south, US Highway 192 (Irlo Bronson Memorial Highway) offers a major east–west commercial corridor, while Osceola Parkway provides access to employment centers and connections toward Orlando International Airport. Additionally, the site has relatively quick access to Florida’s Turnpike and Interstate 4 (I-4), both of which are critical regional highways linking Kissimmee to Orlando, Tampa, and the broader Central Florida region. Overall, the location offers strong local and regional accessibility via a well-established network of major roads and highways.

737 W. Oak Street

1 Space, 1 - 107 ^ppl

(6,706^SF)

From $14,529/MO

The center is situated in a convenient area of Kissimmee, easily accessible from major roads and highways. It's positioned near the heart of the city, providing essential healthcare services to the local community and surrounding areas. The building is likely surrounded by a mix of other medical offices, retail shops, and residential neighborhoods, contributing to a balanced urban environment. With its central location, patients have convenient access to comprehensive cancer care in a supportive setting. The facility is part of a broader network of healthcare providers, ensuring continuity of care and ease of access for those in need of specialized medical services.

103 Broadway

1 Space, 1 - 2 ^ppl

(300^SF)

From $594/MO

The office building is located in Downtown Kissimmee on Broadway. Also, conveniently located within walking distance of Kissimmee City Hall, Osceola County Court House, retail and restaurants in Historic Downtown Kissimmee and Sunrail station. These office spaces are in a 2-Story building on the second floor. The space features a total of 9 offices and 2 restrooms. Great location for any professional office. INCLUDED in rent: CAM fees, electricity and water.

ICON 192

4560 W Irlo Bronson Memorial Hwy

9 Spaces, 1 - 20 ^ppl

(210 - 2,519^SF)

Frontage on US Hwy 192

Ruby Avenue LLC

241 Ruby Ave

1 Space, 1 - 2 ^ppl

(200^SF)

From $750/MO

Unique opportunity! Don't miss out on this professional mini office suite available! These offices are conveniently located in Kissimmee on the Lakefront and close to Kissimmee City Hall, Osceola County Court House, retail and restaurants in Historic Downtown Kissimmee and Sunrail station. These modern office spaces are in a updated 2-Story building. The space features a total of 13 professional offices suites, a lobby, kitchen and 2 restrooms. Great location for any professional office. INCLUDED in rent: CAM fees, electricity and water.

Versatile Office Space for Lease – Ideal for Service & Remote Businesses

1600 E Vine St

1 Space, 3 ^ppl

(600^SF)

A functional and well-equipped space perfect for small teams, service companies, or virtual offices. Whether you're dispatching crews, handling remote work, or need a quiet operational hub, this space offers flexibility without unnecessary overhead. Office spaces highlighted in yellow below Suite E & G. ✨ Property Highlights: Located at the main entrance of NeoCity with a DOT count of 65,000 cars passing by per day 2 separate entrances into the suites for convenience and flexibility. 3 interconnected office spaces fully furnished 1 private office for privacy or management use Outdoor storage shed for tools, inventory, or equipment (more may be negotiated) Optional for a storage container to be brought on-site Storage area inside suite + loft area for additional storage Full kitchenette area Clean private bathroom 5 private parking spaces (more may be negotiated)  Located in the rear section of a professional plaza — ideal for businesses that don’t rely on walk-in traffic or highway exposure. ✅ 1-3-year lease terms available / ✅ 1st month, last month, and Security Deposit Required $4,000/monthly. Perfect for AC repair offices, electrical and plumbing services, dispatch centers, remote teams, and more.

Poinciana Medical Office

1050 Cypress Pkwy

1 Space, 1 - 48 ^ppl

(6,041^SF)

From $12,585/MO

Free-standing medical office building in the Poinciana Towne Center with increasing demand for medical and professional services Situated on Cypress Parkway, with high visibility and surrounding pharmacies, diagnostic centers, and other medical facilities, enhancing referral opportunities and patient convenience Layout consists of multiple 16 exam rooms, 2 physician offices, lab space, a breakroom, 3 large reception areas, and 3 private bathrooms Located 2 miles from HCA Florida Poinciana Hospital, a 177,000-square-foot, 94-bed acute care facility with intensive care services Large building façade signage available facing Cypress Parkway with 44,500 AADT Dedicated parking with additional cross-access parking