Office Space for Rent Port Charlotte

LaPlaya Plaza

2811 Tamiami Trl Ste I

1 Space, 1 - 16 ^ppl

(1,950^SF)

From $2,437/MO

Strategically located along U.S. Route 41 (Tamiami Trail), 2811 Tamiami Trail offers exceptional visibility and direct frontage on one of Port Charlotte’s most heavily traveled commercial corridors. The property is protected by an access road, allowing for safer, more convenient ingress and egress while maintaining strong exposure to passing traffic. Tamiami Trail serves as a primary north-south artery through Charlotte County, connecting Port Charlotte to Punta Gorda and North Port, with easy access to Interstate 75. The surrounding area is home to a mix of national and regional retailers, medical offices, and professional services, generating consistent daily activity. The site benefits from dense nearby residential neighborhoods, providing a strong and stable customer base. With high visibility, controlled access via the frontage road, and placement within a well-established commercial corridor, 2811 Tamiami Trail presents an outstanding opportunity for retail, office, or service-oriented users seeking long-term growth in the Port Charlotte market.

Medical Pavilion Clinic

2525 Harbor Blvd

1 Space, 1 - 51 ^ppl

(6,430^SF)

From $15,137/MO

Sun Wonder Office Plaza

4120 South Tamiami Trail

2 Spaces, 1 - 9 ^ppl

(1,000 - 1,100^SF)

From $1,500/MO

Central Plaza

21234 Olean Blvd

1 Space, 1 - 5 ^ppl

(620^SF)

From $979/MO

Commercial unit available in Central Plaza, Port Charlotte, FL, starting May 5, 2026. This 620 sq ft space offers a flexible layout and is currently configured as a hair salon, making it easy to adapt for medical, legal, or financial office use. Ideally located in the heart of Port Charlotte, just off Tamiami Trail and one block from Fawcett Memorial Hospital, the property provides excellent accessibility and visibility. Ample on-site parking ensures convenience for both clients and staff. The unit includes a washer and dryer, adding extra functionality for a variety of business types. Lease terms of 2 or 3 years are available under a modified gross structure, with tenants responsible only for electricity and communications.

Irongate Plaza

2221 Tamiami Trl

1 Space, 1 - 7 ^ppl

(885^SF)

From $1,593/MO

Prime professional office or retail location with frontage on Tamiami Trail., Port Charlotte, with a direct access! Do not miss this unique opportunity to have your business operating on a busy street, where more then 40K cars passing daily. An ample parking, new AC, new roof. Build out to your needs, and start making money. Water, sewer, condo fee, are included. Modified Gross lease. 2-5 years leases are available.