Office Space for Rent Port Charlotte

12479 S Access Rd

1 Space, 1 - 10 ^ppl

(1,200^SF)

From $1,800/MO

1/2 Mile West of Gasparilla Rd on S Access Rd Port Charlotte

Medical Pavilion Clinic

2525 Harbor Blvd

1 Space, 1 - 51 ^ppl

(6,430^SF)

From $15,137/MO

Sun Wonder Office Plaza

4120 South Tamiami Trail

2 Spaces, 1 - 9 ^ppl

(1,000 - 1,100^SF)

From $1,500/MO

Central Plaza

21234 Olean Blvd

1 Space, 1 - 5 ^ppl

(620^SF)

From $979/MO

Commercial unit available in Central Plaza, Port Charlotte, FL, starting May 5, 2026. This 620 sq ft space offers a flexible layout and is currently configured as a hair salon, making it easy to adapt for medical, legal, or financial office use. Ideally located in the heart of Port Charlotte, just off Tamiami Trail and one block from Fawcett Memorial Hospital, the property provides excellent accessibility and visibility. Ample on-site parking ensures convenience for both clients and staff. The unit includes a washer and dryer, adding extra functionality for a variety of business types. Lease terms of 2 or 3 years are available under a modified gross structure, with tenants responsible only for electricity and communications.

Silvestre Professional Center

3524 Tamiami Trail

1 Space, 1 - 15 ^ppl

(1,890^SF)

From $1,260/MO

Port Charlotte is a dynamic community strategically located along Florida’s Gulf Coast, known for its appealing mix of residential charm and business vitality. As part of the greater Punta Gorda MSA, Port Charlotte attracts both locals and visitors seeking a high quality of life, with its proximity to beautiful Gulf beaches, lush parks, and the scenic Charlotte Harbor. The area’s population is growing steadily, fueled by new developments such as Sunseeker Resort, affordable living options, and a strong influx of retirees, families, and seasonal residents. With Tamiami Trail (US-41) serving as the primary commercial corridor, Port Charlotte boasts a wealth of retail options, restaurants, and entertainment venues that benefit from substantial daily traffic. Businesses in Port Charlotte enjoy a diverse clientele, thanks to its balanced demographic profile that combines local residents, tourists, and commuters.