Office Space for Rent Frederick County

HQ Frederick - East 4th St

241 East 4th Street 1st Floor

5 Spaces, 7 ^ppl

Coworking from $129/MO

East 4th Street in Frederick offers a vibrant blend of historic charm and modern convenience, making it an ideal location for flexible coworking spaces. Nestled in the heart of downtown, this street provides easy access to various cafes, restaurants, and local shops, creating a lively atmosphere that encourages productivity and networking. The area's walkability and proximity to public transit make commuting hassle-free, while the mix of classic architecture and contemporary amenities supports a professional yet welcoming environment. East 4th Street's community feel attracts entrepreneurs, freelancers, and small businesses looking for workspace beyond the typical office. With its blend of accessibility and character, this location offers more than just a desk—it connects to Frederick's thriving business scene and culture.

KeyPark Center

1050 Key Parkway

4 Spaces, 1 - 52 ^ppl

(1,349 - 6,441^SF)

From $2,023/MO

1050 Key Parkway is located next to the Rite Aid on Baughmans Lane. The property is conveniently located just around the corner from the ramps to Route 15 North and South and all the shopping, restaurants and amenities of Route 40.

Governors Place Medical Center II

108 Thomas Johnson Drive

3 Spaces, 1 - 140 ^ppl

(2,500 - 17,500^SF)

112 Thomas Johnson Drive sits prominently along the street frontage, in close proximity to over 200 other businesses and medical practices. The property is approximately one mile from the gate to Fort Detrick and approximately two miles from Frederick Health Hospital and Historic Downtown Frederick.

7100 Guilford

7100 Guilford Drive

1 Space, 1 - 160 ^ppl

(3,200^SF)

From $5,866/MO

7100 Guilford Drive is located at the intersection of Guilford Drive and New Design Road directly adjacent to the shopping center with Best Buy and WalMart. The property is situated along Route 70 with great highway visibility.

915 Toll House Ave

5 Spaces, 1 - 26 ^ppl

(1,621 - 2,518^SF)

Surrounded by a variety of medical practices, neighborhood retail centers and residential development, this site is surrounded by amenities and close to historic downtown Frederick. Within walking distance to Frederick Health System, with Hood College and Ft Detrick nearby, this location is well situated for a variety of medical practices.

The Valley Register

123 W Main St

1 Space, 1 - 6 ^ppl

(800^SF)

From $1,500/MO

Shared space available. Short lease optional. This historic building offers an office / retail space. 800 Sq. Ft. in the heart of Main St. Middletown. Perfect for Therapist / counselor Tutor or test-prep center Accountant / bookkeeper Real-estate or mortgage office Insurance agent Attorney (solo) Massage / wellness (if zoning allows) Small nonprofit / local org Remote professional tired of working from home