Photo 1 of 301 Broadway St, Cape Girardeau, MO 63701
Photo 2 of 301 Broadway St, Cape Girardeau, MO 63701
Photo 3 of 301 Broadway St, Cape Girardeau, MO 63701

Office Space at 301 Broadway St in Cape Girardeau

301 Broadway St, Cape Girardeau, MO 63701

301 Broadway is centrally located in the heart of downtown Cape Girardeau, one of Southeast Missouri’s most vibrant and walkable business districts. The property sits among a dynamic mix of restaurants, retail, and entertainment venues, offering convenience and energy for both employees and clients.

The historic Missourian Building has long been a cornerstone of the community and continues to serve as a hub for business and media activity. Its prime location places tenants within walking distance of key amenities and just minutes from major transportation routes.

Strategically positioned between St. Louis and Memphis, Cape Girardeau provides regional accessibility while maintaining a strong local workforce and business environment. Nearby parking and multiple access points make commuting and client visits simple and efficient.

301 Broadway St Office Space for Rent

1 Space Available
Property Details
Property Type
Office
Property Size
21,507 sqft
Last Updated
4/21/2026
Landlord's Leasing Agent Representative

Matt Huber

(573) 334-5200

301 Broadway St location
City
Cape Girardeau
Zip Code
63701