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Office Space for Rent Durham County

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Spaces Durham - Mangum St

555 S Mangum Street Suite 100

3 Spaces , 1 - 29 ^ppl

$299 - $429^/MO

The business center in Mangum Street is part of a landscape-changing new development at the heart of Durham city centre a mainline into the business world of North Carolina and beyond. This is a workspace for creative professionals, dynamic corporate players, and graduating entrepreneurs from nearby Duke University. It facilitates these change-makers with its fantastic selection of private offices, meeting rooms and flexible workspaces. From the site’s rooftop terrace, you overlook the Durham Bulls Athletic Park stadium, with a view so good, you could almost catch a home run right from your office. But even if you are not a sports fan, the relaxed vibe and casual atmosphere can help you feel at home here. Creature comforts are enhanced by the super-fast Wi-Fi connections, barista-brewed coffee, and friendly reception staff ready to help you achieve your goals.

Turnkey Space with New HVAC, Flooring & Paint

1804 Martin Luther King Junior Parkway

1 Space, 1 - 8 ^ppl

(1,000^SF)

I-40 exit 270 to 15-501 towards Durham, exit 105B to Martin Luther King Jr Pkwy, property is in the left.

High-Visibility Office Suites Near RTP – 1,100 SF in Prime Durham Location

1910 Sedwick Rd, BLDG 500

1 Space, 1 - 9 ^ppl

(1,100^SF)

This property is located in a prime Durham area, just minutes from RTP and easily accessible via Hwy 55, Hwy 54, and I-40. Surrounded by a variety of restaurants and shops.

Suite C | 1,030 SF Office Suite in Prime Durham Location

1910 Sedwick Rd

1 Space, 1 - 8 ^ppl

(1,030^SF)

From $1,545/MO

This property is located in a prime Durham area, just minutes from RTP and easily accessible via Hwy 55, Hwy 54, and I-40. Surrounded by a variety of restaurants and shops.

706 Ninth Street

1 Space, 1 - 29 ^ppl

(1,500^SF)

Close proximity to Duke University and Medical Center, Durham VA Medical Center, Downtown Durham, NC-147, I-85

Imperial Tower

4820 Emperor Boulevard

6 Spaces, 1 - 246 ^ppl

(up to 30,827^SF)

North Carolina's Largest and Most Visible Office Building on I-40

433 W. Main Street

1 Space, 1 - 45 ^ppl

(5,676^SF)

Located in the heart of Downtown Durham, a walkable location in close proximity to numerous restaurants, retail, amenities and parking.

110 E. Carver Street

1 Space, 1 - 38 ^ppl

(4,769^SF)

From $9,339/MO

The property sits in close proximity to Duke Regional Hospital (±0.3 miles) and is a short distance from I-85 (±1.5 miles), downtown Durham (±3.5 miles), and Duke University (±4 miles).

2919 Colony Road

1 Space, 1 - 31 ^ppl

(3,867^SF)

400 Park Offices

400 Park Offices Drive

1 Space, 1 - 8 ^ppl

(959^SF)

From $3,995/MO

Located in the heart of the Research Triangle Park on Hwy. 54 near Davis Drive

Downtown Durham Office/Retail Condo

204 Rigsbee Ave, Suite 101

1 Space, 1 - 32 ^ppl

(3,944^SF)

Located in the City Center District of downtown Durham, 204 Rigsbee sits along a stretch of some of the City’s most popular restaurants and bars. It is also just a short walk to the Central Park District, with its numerous apartments and food and beverage options. Nearby, the American Tobacco Campus beckons with its unique mix of offices, restaurants, and entertainment. The famed Durham Performing Arts Center hosts world-class performances, and the Durham Bulls Athletic Park hosts over 500,000 fans during the baseball season. Duke University and the Duke University Medical Center are just a short drive away.

Croasdaile Office Park

1816 Front Street, Suite 220

1 Space, 1 - 24 ^ppl

(3,000^SF)

From $4,687/MO

Located in north Durham, Croasdaile Office Park is surrounded by a variety of retail and service businesses and offers convenient access to I-85/US 70 (±0.2 miles), Duke University/Medical Center (±2 miles), and downtown (±4 miles).

1212 Broad Street, Suite B

1 Space, 1 - 11 ^ppl

(1,356^SF)

n/a

Bristol Place

4819 Emperor Blvd.

3 Spaces, 1 - 138 ^ppl

(6,225 - 17,278^SF)

From $15,822/MO

A four-story office building located in the award-winning Imperial Center Business Park. Minutes from I-40, I-540, RDU International Airport and numerous surrounding amenities.

Winchester Place

4309 Emperor Blvd.

5 Spaces, 1 - 159 ^ppl

(3,058 - 19,863^SF)

From $7,517/MO

A four-story building located in the award-winning Imperial Center Business Park. Minutes from I-40, I-540, RDU International Airport and numerous surrounding amenities.

Park City

2222 NC 54

5 Spaces, 1 - 158 ^ppl

(4,509 - 19,792^SF)

From $10,708/MO

Park City West is a redeveloped Class A Office property incorporating modern enlightened design with indoor and outdoor work environments. Experience firsthand how collaborative and healthy workspaces inspire opportunities for innovation.

Regus Durham - Meridian Pkwy

2530 Meridian Parkway Suite 300

3 Spaces, 1 - 41 ^ppl

(up to 30,000^SF)

Coworking from $209/MO

This state of the art and fully functional business center installation is set within a contemporary landmark office building with an impressive frontage and a stylish architectural design. This center provides a range of flexible serviced office space to cater for any type or size of specific corporate business need and workspace requirement. Inside, this center is fully furnished and air conditioned. The building also offers a wide range of fantastic facilities and professional provisions including spacious meeting rooms, conferencing capabilities, high speed internet connectivity, dedicated corporate telephony and more.

HJK LLC

1912, North Carolina 54

1 Space, 10 ^ppl

(3,200^SF)

From $450/MO

Professional Office / Flex Space Available in RTP – Flexible Lease Options: Discover a premium office/flex space in the heart of Research Triangle Park (RTP), comprising Suite C (2,500 sq. ft.) and Suite C2 (700 sq. ft.). These highly versatile suites can be leased separately or together, offering the perfect solution for growing teams, satellite offices, or multiple departments seeking professional, efficient, and flexible workspace. Property Details • Address: 1912 E NC Hwy 54, Suites C & C2, Durham, NC 27713 • Suite Sizes: Suite C = 2,500 sq.ft| Suite C2 = 700 sq.ft • Total Available Space: 3,200 sq.ft • Availability: February 1, 2026 • Use: Office / Flex

Venture X

600 Park Offices Drive Suite 300

4 Spaces, 1 - 20 ^ppl

Coworking from $99/MO

The modern designed space has high exposed ceilings with an industrial loft design, a large lounge area with a café and hi-tech meeting rooms, and high-speed internet. This location in Durham is a modern coworking space offering its members a shared, flexible workspace with a community of like-minded business professionals. Members include entrepreneurs, established businesses, startups, and small- to medium-sized businesses. Dedicated community managers provide boutique hotel-style hospitality, advocating for your business success with concierge-level member services and 24/7 secure access. This space also houses a fully furnished wellness room specifically designed for new working mothers or those in need of a private space to tend to other personal health needs.

Regus Durham - Shannon Rd

3511 Shannon Road

4 Spaces, 7 ^ppl

Coworking from $149/MO

This modern office space has a range of social coworking areas and serviced offices available, all come fully equipped with beautiful furniture and are ready to move into. The center is accessible 24 hours a day so the clients can work flexibly. This workspace has spacious meeting rooms completely filled with natural lights to keep the members energetic and enthusiastic. Moreover, this workspace provides an abundance of amenities such as high-speed internet, a business lounge, break-out areas, copying, and printing facilities. In addition, a kitchen is also available inside the building where members can grab snacks and beverages.

Regus Durham - Emperor Blvd

4819 Emperor Boulevard Suite 400

3 Spaces, 1 - 12 ^ppl

(up to 30,000^SF)

Coworking from $229/MO

This prestigious and contemporary business center installation offers all prospective tenants and professionals with a prominent business address that features individual offices, suites and team rooms which are ideal to fulfil any type of corporate requirement. The center's contemporary décor supports the RTP cutting-edge image. It includes three technologically equipped and spacious meeting rooms and a training center ideal for a number of training functions and professional purposes. The site also features high speed internet, dedicated corporate telephony, copy and printing equipment and much more.

Durham Bottling Co

506 Ramseur Street Suite 1

2 Spaces, 1 - 5 ^ppl

(up to 12,000^SF)

Coworking from $300/MO

The center is dedicated to building a membership base and an environment that is welcoming, impactful, and growing. More than just technology, the center is dedicated to providing a useful and secure home base for non-profits, freelancers, creatives, entrepreneurs, new small enterprises, and teams as they grow into the powerful roles that they will undoubtedly play in the city and beyond. It is transformed into a modern industrial workspace that has dynamic seating options, private corners, meeting space, conference rooms, dedicated event space, and a wide selection of private office suites. Large windows and skylights help light the space through the day, and warm lamps and varied lighting illuminate in the evening the night owls. In addition, the workspace allows clients to have 24-hour access 7 days out of every week with high-speed Wi-Fi accessible all through the center.

3LO

120 East Parrish Street Suite 310

2 Spaces, 1 - 15 ^ppl

(up to 1,200^SF)

Coworking from $199/MO

Nestled in the heart of Downtown Durham’s historic City Center district, this inspiring co-working and meeting hub offers the perfect blend of functionality, collaboration, and aesthetic appeal. Located in the iconic Law Building on the renowned Black Wall Street, the space is surrounded by vibrant energy, including trendy restaurants, startups, venture capital firms, and local landmarks like DPAC just two blocks away.

WeWork Durham - Corcoran St

110 Corcoran Street One City Center

3 Spaces, 1 - 100 ^ppl

(up to 29,167^SF)

Coworking from $250/MO

The refined design and stunning landmark architecture are locally renowned as a commercially significant business establishment incorporating a neutral palette, international style, and industrial materials to create an elegant and fun workspace. The center has top-notch amenities like fully stocked printing and private phone booths. Tenants can even bring their dogs. Spacious, fully-furnished offices offer a team somewhere to work comfortably, where members can move in and get started straight away - no need for time wasted setting up various desks. This stylish contemporary building has an entrance that makes a statement as the first impression for guests.

1904 Front St

4 Spaces, 1 - 14 ^ppl

(144 - 1,706^SF)

From $3,554/MO

Convenient access to I-85, US RTE 501 and NC-HWY 147 Minutes from Downtown Durham and Durham Central Park, Durham Bulls Athletic Park, Durham Performing Arts Center (DPAC), and American Tobacco Campus Conveniently located near the Durham Convention Center for meetings and conferences Easy access to Northgate Mall, Research Triangle Park and nearby shopping and dining centers