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Office Space for Rent Berks County

Wyomissing Hills Professional Center

320 Abington Dr

1 Space, 1 - 22 ^ppl

(1,200^SF)

Located in desirable Wyomissing with frontage along heavily trafficked State Hill Road. The Wyomissing Hills Professional Center enjoys easily access to the local road system and is centrally located in Berks County providing it with a convenient location for professional office uses.

Exeter Medical Professional Building

6 Hearthstone Ct

5 Spaces, 1 - 23 ^ppl

(1,516 - 2,818^SF)

From $126/MO

6 Hearthstone Court is now under new ownership with a commitment to raising the level of quality offered at this professional office building. Medical and general office suites are available. New ownership is planning renovations to building common areas, parking lot and building exterior. If you are in the market for office space in the Exeter Township area this property should be in consideration. Visit naikeystone.com for accurate listing info.

590 Oley Road

1 Space, 1 - 25 ^ppl

(3,108^SF)

Position your business in the heart of Oley with this attractive and well-maintained space offering a professional environment in a convenient, highly accessible location. The suites feature a blank canvas for you to create your office setting to your liking.

517 E Lancaster Ave

517 East Lancaster Avenue

1 Space, 1 - 30 ^ppl

(3,777^SF)

This building is situated along the busy East Lancaster Avenue, which is a main thoroughfare connecting various parts of Shillington and the surrounding areas. The avenue is lined with shops, small businesses, and service providers, giving the location great visibility and accessibility. There are also various restaurants, cafes, and other amenities nearby, making it easy for clients/patients to run errands or grab a bite before or after appointments. Visit naikeystone.com for accurate listing info.

1025 Berkshire Blvd

1025 Berkshire Blvd Ste 600

1 Space, 1 - 24 ^ppl

(3,000^SF)

From $4,500/MO

Discover the vibrant community surrounding the property in Wyomissing, PA. With its prime location and close proximity to local businesses and amenities, this bustling area presents an ideal opportunity for your next office space. Visit naikeystone.com for accurate listing info.

4641 Pottsville Pike

2 Spaces, 1 - 16 ^ppl

(1,415 - 2,000^SF)

Located conveniently at the Rt. 222 & Rt. 61 interchange. Visit naikeystone.com for accurate listing info.

985 Berkshire Boulevard

1 Space, 1 - 18 ^ppl

(2,225^SF)

From $2,874/MO

Located along the highly traveled Berkshire Boulevard corridor in the heart of Wyomissing, 985 Berkshire Blvd benefits from immediate access to Route 222 and Route 422, positioning it within one of Berks County’s most active retail and medical hubs. The property is surrounded by national retailers, healthcare providers, and dense residential neighborhoods, with over 200,000 residents within a 5-mile radius. The site is further enhanced by its proximity to the transformative Broadcast District, a premier 100+ acre mixed-use development currently underway. The project is planned to deliver over 115,000 SF of upscale retail anchored by Whole Foods Market, alongside a curated mix of national tenants including Sephora, Shake Shack, First Watch, and BJ's Restaurant & Brewhouse. Upon completion, the Broadcast District will introduce approximately 700–800 residential units, a hotel component, and walkable green spaces, creating a true live-work-play environment that will significantly increase daytime traffic and consumer demand in the immediate trade area. Visit naikeystone.com for accurate listing info.

White Pines Corporate Center

2433 Morgantown Road

1 Space, 1 - 28 ^ppl

(3,548^SF)

2433 Morgantown Road offers prime visibility along Route 10 in Reading, one of Berks County’s primary commercial corridors. The property provides immediate access to U.S. Route 422, Interstate 176, and the Pennsylvania Turnpike, enabling convenient regional connectivity. Offering strong traffic counts, excellent accessibility, and a dense residential and workforce base. Ideal for professional or medical office users seeking a high-exposure Berks County address. Visit naikeystone.com for accurate listing info.

2758 Century Boulevard

1 Space, 1 - 23 ^ppl

(2,832^SF)

Well-located medical office space in Wyomissing’s established medical corridor, adjacent to major healthcare providers including the Surgical Institute of Reading. Ideal for physician practices, specialty clinics, or outpatient services. Convenient access, ample parking, and strong medical synergy in a highly desirable professional setting. Visit naikeystone.com for accurate listing info.

1260 Broadcasting Road

1 Space, 1 - 40 ^ppl

(4,939^SF)

Easily accessible from major roadways, the property in Wyomissing, PA, offers convenient transportation links for tenants and visitors alike. With its central position and array of nearby attractions, Wyomissing offers an exceptional setting for your office activities and provides a thriving environment for your business. Visit naikeystone.com for accurate listing info.

Literacy Council of Reading

35 S Dwight St

1 Space, 1 - 35 ^ppl

(2,187^SF)

From $2,642/MO

This sought-after area is in close proximity to well-connected routes, including Route 422 and Route 222, providing seamless transportation links for businesses and commuters. The property's strategic location offers excellent visibility and accessibility, making it an attractive choice for office and office building investors seeking a well-connected and easily accessible location for their ventures. Visit naikeystone.com for accurate listing info

200 Berkshire Commons

2201 Ridgewood Road

1 Space, 1 - 50 ^ppl

(6,200^SF)

Immerse your business in the vibrant office complex of 200 Berkshire Commons, Wyomissing, PA. This upscale medical and business complex offers a dynamic location for professionals and businesses alike. With a strategic location off of Berkshire Blvd, the office lends its self to easy access to all major road ways being in the center of Wyomissing Commerce. Visit naikeystone.com for accurate listing info.

925 Berkshire Blvd

925 Berkshire Boulevard

1 Space, 1 - 84 ^ppl

(4,000^SF)

From $5,166/MO

Located in the Wyomissing Professional Center, 925 Berkshire Blvd is a Class A multi tenant building that offers an ideal location for any owner user or investor. Visit naikeystone.com for accurate listing info.

300 Berkshire Commons

2201 Ridgewood Road Suite 330

1 Space, 1 - 13 ^ppl

(1,631^SF)

2201 Ridgewood Road is located in the heart of Wyomissing, Pennsylvania, one of Berks County’s premier medical and professional office markets. The property is situated within a well-established office condominium community, surrounded by a dense concentration of medical practices, professional offices, and residential neighborhoods. Visit naikeystone.com for accurate listing info.

Wyomissing Professional Center

999 Berkshire Blvd

2 Spaces, 1 - 123 ^ppl

(3,078 - 15,435^SF)

This Multi-Tenant Office Building is located in the Wyomissing Professional Center of Wyomissing PA. A mixed use office and medical campus in the Borough of Wyomissing area of Greater Reading. The Campus offers easy access to Rt. 422 and Rt. 222. In addition, the Campus is within close proximity to hotels, restaurants, and entertainment.

Wyomissing Professional Center

875 Berkshire Blvd

1 Space, 1 - 17 ^ppl

(2,115^SF)

Wyomissing Professional Center, located along prosperous Berkshire Boulevard, offers the numerous amenities. High visibility and access to major roadways and spacious parking are offered. A Day Care facility is located within the center. It is in close proximity to major hotels and public transportation. Convenient to shopping areas. It sits on well-landscaped grounds and fiber-optic communications are readily available.

1121 Snyder Road

1 Space, 1 - 44 ^ppl

(5,500^SF)

From $6,416/MO

Well located, professional office building with unique opportunities for clean space or lab room type operations, or suitable for professional office/administration. Nearby restaurants and Giant Grocery anchored shopping center offer good amenities for employees. Easy access to both 222 Hwy and 422 Hwy roads. Space notes: Former IT management and security space with private offices, conference room, kitchenette, clean rooms, ADA compliant restrooms, and pull up parking. The space has 13' clear floor to deck height with a 9' drop ceiling. Possibilities for converting to flex space. Visit naikeystone.com for accurate listing info.

1020 James Drive

2 Spaces, 1 - 22 ^ppl

(1,569 - 2,794^SF)

From $1,634/MO

Professional Office Building with two first floor spaces available for lease. Easy access off Rte 183 near the Wawa, about a 1/4 mile from the 222 Hwy interchange. Building is perfect for professional services or medical practices. Visit naikeystone.com for accurate listing info.

Berkshire Court Professional Bldg

50 Berkshire Ct

1 Space, 1 - 21 ^ppl

(2,600^SF)

From $4,766/MO

Well maintained professional office building in the heart of the Wyomissing, PA business district. Professional and medical services in the immediate area, along with access to shopping, restaurants and a block away from Starbucks. Very close to the areas highway systems with good access to all the main roads. Visit naikeystone.com for accurate listing info.

220 N. Park Rd.

1 Space, 1 - 480 ^ppl

(60,000^SF)

NAI Keystone is pleased to exclusively represent Park Place Center in Wyomissing, PA in leasing a newly proposed 60,000 Sq. Ft. Office/Medical/Research building as Phase 1 of a multi-phase project. Park Place Center is a ten acre site within walking distance of the former VF Outlets that is now part of The Knitting Mills, an exciting new $100 million redevelopment mixed-use business and retail campus.

3855 Penn Ave

1 Space, 1 - 57 ^ppl

(7,072^SF)

3855 Penn Avenue is a well-positioned medical office location in the heart of Sinking Spring, one of Berks County’s most established and desirable healthcare corridors. The property offers excellent visibility and immediate access along Penn Avenue (US-422 Business), a heavily traveled arterial connecting West Reading, Wyomissing, and the Greater Reading market. The site benefits from close proximity to major healthcare anchors, including Reading Hospital – Tower Health, Penn State Health St. Joseph, and a dense concentration of medical, dental, and outpatient specialty practices. The surrounding area features strong residential demographics, providing a built-in patient base and consistent demand for medical services. Convenient access to US Route 422 and Route 222 allows for efficient regional connectivity, while ample nearby parking and signalized intersections enhance ease of patient ingress and egress. The location is ideal for primary care, specialty clinics, outpatient services, therapy, imaging, or ancillary medical uses seeking a highly visible, accessible, and established medical setting. Visit naikeystone.com for accurate listing info.