Office Space for Rent Longwood

Second Floor Medical Space | Immediate Hospital Proximity

451 South Milwee Street

1 Space, 1 - 24 ^ppl

(3,000^SF)

From $6,500/MO

Strategically positioned at the signalized intersection of SR 434 and Milwee Street, this location offers exceptional visibility and accessibility in the heart of the Longwood/Altamonte Springs corridor. SR 434 is a major east–west thoroughfare connecting I-4 to Semoran Boulevard (SR 436), providing seamless access throughout Central Florida and strong daily traffic counts. Located directly next door to Orlando Health South Seminole Hospital, the property benefits from immediate proximity to a full-service hospital, creating a highly synergistic environment for medical users. This adjacency enhances patient convenience, strengthens referral networks, and supports a steady flow of healthcare demand. Surrounded by established residential communities, dense daytime population, and a strong mix of medical and professional users, the site is ideally suited for healthcare providers seeking both visibility and accessibility. Patients and staff benefit from easy ingress/egress, nearby retail and dining amenities, and close proximity to I-4, providing quick connectivity to Orlando, Maitland, and the greater Central Florida market. This is a premier medical location within a proven healthcare corridor—ideal for both established practices and growing providers.

Freestanding Building

1665 EE Williamson Road

1 Space, 1 - 77 ^ppl

(9,648^SF)

From $11,256/MO

Between Markham Woods Road and I-4

Coworkers Zone LLC

2941 W State Rd 434 Longwood

3 Spaces, 1 ^ppl

Located at 2941 W SR 434, Longwood, FL, Corworkers Zone offers a modern and flexible coworking environment designed to meet the needs of entrepreneurs, remote workers, and small businesses. Our space includes: ✅ Large Private Office – Available for rent by half-day or full-day, perfect for focused work or client meetings. ✅ Meeting Room – A professional space for team discussions, presentations, or brainstorming sessions. ✅ Two Dedicated Desks – Ideal for those seeking a consistent and inspiring workspace. Whether you need a quiet office for the day, a collaborative meeting room, or a dedicated desk, Corworkers Zone provides the perfect setting for productivity and success.

Sanlando Center II

2180 W State Road 434

5 Spaces, 1 - 17 ^ppl

(1,392 - 4,901^SF)

From $2,320/MO

Sanlando Center I

2170 W State Road 434

8 Spaces, 1 - 83 ^ppl

(1,322 - 10,408^SF)

From $2,320/MO

Suite 385

Blackadar Park

1404-1436 North Ronald Reagan Blvd

3 Spaces, 1 - 28 ^ppl

(1,575 - 3,528^SF)

Midway between SR 434 & General Hutchinson Pkwy on Ronald Reagan Blvd (CR 427)