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Office Space for Lease South Dakota

Regus Sioux Falls - North Cherapa Pl

300 N Cherapa Place 2nd Floor

5 Spaces, 6 ^ppl

Coworking from $69/MO

A newly constructed six-story office building designed to accommodate a wide range of professional needs. The property offers flexible workspace options, including fully serviced private offices, team suites, and open coworking areas, all thoughtfully designed to encourage efficiency, focus, and collaboration. Modern interiors feature high-quality finishes, ample natural light, and adaptable layouts suitable for businesses of varying sizes. The building forms part of a mixed-use campus that integrates residential living, dining options, and everyday conveniences, creating a seamless work-life environment. On-site amenities support productivity and comfort throughout the workday, making the building well suited for growing companies, remote teams, and established organizations alike.

Regus Sioux Falls - Sout Reid St

101 S Reid Street Suite 307

3 Spaces, 1 - 6 ^ppl

Coworking from $429/MO

Sioux Falls has a long history as a pioneering city, and these office premisses are ideal for forward-thinking businesses. They are based in a LEED-certified, environmentally friendly building, right at the heart of downtown Sioux Falls. The offices are modern but remarkably well integrated with the surrounding environment. The large windows provide a polished look to the building whilst letting natural light fill the indoor space, and they also offer outstanding views of the Big Sioux River just outside.

817 W. Russell Street

1 Space, 1 - 42 ^ppl

(5,292^SF)

From $5,292/MO

Located west of downtown, near the airport area and along W. Russell Street. Russell St. Traffic Count: 26,800 VPD

530 South Phillips Avenue

1 Space, 1 - 18 ^ppl

(2,264^SF)

From $3,396/MO

Downtown Sioux Falls Access to Phillips Ave and 14th St

409 E 41st St

1 Space, 1 ^ppl

(120^SF)

Located near Roxi & Co, Polar Bites, Balance Life Massage Therapy, Tranquility Therapeutic Massage & Spa, Insights Rehab Counseling, Molly Maid of Sioux Falls, Recharge, Corner Stone School, Nyberg's ACE Handyman Services, Vanessens Salon & Suites

Suite 160 For Sublease

2600 W. 49th Street

1 Space, 1 - 13 ^ppl

(1,667^SF)

From $2,500/MO

Located on the corner of 49th Street and Kiwanis Avenue Co-tenants include Solarity, Vance Thompson Vision, Computer Forensic Resources, & South Dakota State Medical Association Area neighbors include NAI Sioux Falls, Helpline Center, Children's Dental Center, Voyage Federal Credit Union, Sioux Falls Parks & Rec, Runnings

5604 W. 41st Street

1 Space, 1 - 22 ^ppl

(2,700^SF)

From $2,249/MO

Located on 41st Street west of Marion Road Area neighbors include Kappenman Family Dental, Lewis Drug, US Bank, Wells Fargo Bank 41st Street Traffic Count: 17,700 vpd

4205 W. 53rd Street

2 Spaces, 1 - 32 ^ppl

(2,715 - 3,977^SF)

From $2,262/MO

Located northwest of the intersection at 57th & Louise Area neighbors include New Beginnings Faith Church, Avera, D'Luxe Suites, Levo Credit Union, USPS South Carrier Annex, Empire Mall, INTEX Cleaning & Restoration Easy access to I-229

100 N. Krohn Place

1 Space, 1 - 3 ^ppl

(400^SF)

Located between E. 10th Street and E. 8th Street on N. Krohn Place Area neighbors include Caribou Coffee, Take 5 Oil Change, Taco John's, Boys & Girls Clubs of the Sioux Empire, Children's Home Shelter, Casey's, GreatLIFE

Simpson Building

102 N Krohn Pl

4 Spaces, 1 - 3 ^ppl

(140 - 294^SF)

Located in eastern Sioux Falls, the area surrounding the property is known for its bustling business community. With easy access to I-229 and public transit, the location provides convenience for both employees and clients. Prospective Office / Office Building tenants will appreciate the amenities that the area has to offer, making it an ideal choice for their business needs. Nearby attractions and businesses include the beautiful Falls Park, the lively SculptureWalk, Caribou Coffee, Last Stop CD Shop and Popeyes.

Summit Properties Offices

47392 272nd St, Suite 3-5

1 Space, 1 - 8 ^ppl

(1,000^SF)

South on Highway 115 (Minnesota Ave) out of Sioux Falls, turn west on 272nd Street, building on north side of 272nd Street

Falls Center, Suite 330 Office Suite

431 North Phillips Avenue

1 Space, 1 - 15 ^ppl

(1,820^SF)

This prime downtown location offers easy access to a variety of amenities and attractions. Enjoy the convenience of being just steps away from well known coffee shops, The Source and La Luna Cafe , perfect for client or team meetings. Take advantage of the dynamic cultural scene with the nearby Old Courthouse Museum and Sculpture Walk. For a breath of fresh air, stroll along the serene paths of Falls Park or explore the many boutiques and shops in the area. The possibilities are endless in this thriving locale, making it an ideal choice for your new office space.

310 S 1st Ave

1 Space, 1 - 107 ^ppl

(13,404^SF)

From $17,871/MO

Discover the vibrant surroundings of this prime downtown Sioux Falls location. Situated in the heart of the city, the area is surrounded by a dynamic mix of businesses, restaurants, and attractions.

3411 S Hawthorne Ave, Suite A

1 Space, 1 - 8 ^ppl

(1,025^SF)

Located just east of Western Avenue near 41st Street Area neighbors include Western Mall, Scheel's, Graham Tire, Black Hills Federal Credit Union, Montgomery's, Combined Pool & Spa, Audio Playground Electronics

Dunes Business Suites

600 Stevens Port Dr

3 Spaces, 1 - 2 ^ppl

(158 - 239^SF)

Dakota Dunes, SD

Gold Circle

400 Gold Circle, Ste 130

1 Space, 1 - 10 ^ppl

(800^SF)

From $1,333/MO

Just off I-29 South Dakota Exit 1 at the intersection of Dakota Dunes Boulevard & Sioux Point Road

Centennial | Offices

300 Centennial Dr

3 Spaces, 1 - 57 ^ppl

(1,233 - 7,100^SF)

From $1,027/MO

Located just off Interstate 29 in the Gateway Business Park

1809 N. Terin Circle

1 Space, 1 - 22 ^ppl

(2,803^SF)

From $2,803/MO

Located in west Sioux Falls between Madison Street and Russell Street Easy access to I-29 Neighbors include Five Star Storage, Jay's Body Shop, Knife River-South Dakota and more.

Jameson Office

3500 S. Phillips Avenue

1 Space, 1 - 17 ^ppl

(2,153^SF)

From $2,511/MO

Building located on the Southeast corner of E. 43rd Street and S. Phillips Avenue Easy access to Minnesota Avenue, Interstate 229 and 41st Street

1610 N Minnesota Avenue Office

1 Space, 1 - 39 ^ppl

(4,877^SF)

From $7,112/MO

Located on North Minnesota Avenue just south of the Sioux Falls Airport Area neighbors include A&B Business Solutions, Levo Federal Credit Union, US Bank, Kum & Go, Xcel Energy, Bell Incorporated, Sioux Falls Regional Airport Minnesota Avenue Traffic Count: 11,800 vpd

4320 S. Louise Avenue, 200

4320 South Louise Avenue

1 Space, 1 - 13 ^ppl

(300^SF)

Located on Louise Avenue just south of the Empire Mall Area neighbors include Five Guys, Caribou Coffee, The Empire Mall, Popeyes Louisiana Kitchen, Levo Credit Union, Pomegranate Market, Qdoba, GreatLIFE Woodlake Louise Avenue Traffic Counts: 22,100 vpd

100 S. Spring Avenue

2 Spaces, 1 - 12 ^ppl

(583 - 1,453^SF)

Conveniently located at 9th Street and Spring Avenue Close proximity to downtown and core area

1600 S. Western Avenue, Suite C

1 Space, 1 - 6 ^ppl

(788^SF)

Located within Park Ridge Galleria at 26th & Western Avenue Co-tenants include: The Dive, Grille 26, Liquor Falls, Volin's Racquet & Soccer, Barbara's Needlepoint, HobbyTown, Park Ridge Shoe Repair

122 East Sioux Ave

122 E Sioux Ave

1 Space, 1 - 5 ^ppl

(500^SF)

From $595/MO

Available Now -Approximately 500 sq. ft. available now on Sioux Ave in Pierre, SD — a high-visibility area. • Public Restroom in building • Large Street Front Signage Available at No Charge • Prime Location with high visibility at 122 East Sioux Ave in Pierre • Bright, inviting office space with abundant windows, natural light, and outdoor views • Great fit for office or small business • Rent: $595 a month

Gas Co. Building

114 S. Main Avenue

1 Space, 1 - 20 ^ppl

(2,467^SF)

From $3,702/MO

Located in the heart of downtown Sioux Falls Building tenants: McGough Construction, Felsburg, Holt & Ullevig Area neighbors include: CCC Information Services, First Dakota National Bank, Hotel on Phillips Sioux Falls, and Woodgrain Brewing Co.