Narrow your search

Search nearby for more results

Office Space for Lease South Dakota

Regus Sioux Falls - North Cherapa Pl

300 N Cherapa Place 2nd Floor

5 Spaces, 6 ^ppl

Coworking from $69/MO

A newly constructed six-story office building designed to accommodate a wide range of professional needs. The property offers flexible workspace options, including fully serviced private offices, team suites, and open coworking areas, all thoughtfully designed to encourage efficiency, focus, and collaboration. Modern interiors feature high-quality finishes, ample natural light, and adaptable layouts suitable for businesses of varying sizes. The building forms part of a mixed-use campus that integrates residential living, dining options, and everyday conveniences, creating a seamless work-life environment. On-site amenities support productivity and comfort throughout the workday, making the building well suited for growing companies, remote teams, and established organizations alike.

Regus Sioux Falls - Sout Reid St

101 S Reid Street Suite 307

3 Spaces, 1 - 6 ^ppl

Coworking from $399/MO

Sioux Falls has a long history as a pioneering city, and these office premisses are ideal for forward-thinking businesses. They are based in a LEED-certified, environmentally friendly building, right at the heart of downtown Sioux Falls. The offices are modern but remarkably well integrated with the surrounding environment. The large windows provide a polished look to the building whilst letting natural light fill the indoor space, and they also offer outstanding views of the Big Sioux River just outside.

Dunes Business Suites

600 Stevens Port Dr

5 Spaces, 1 - 2 ^ppl

(158 - 298^SF)

Dakota Dunes, SD

Gold Circle

400 Gold Circle, Ste 130

1 Space, 1 - 10 ^ppl

(800^SF)

From $1,333/MO

Just off I-29 South Dakota Exit 1 at the intersection of Dakota Dunes Boulevard & Sioux Point Road

Centennial | Offices

300 Centennial Dr

3 Spaces, 1 - 57 ^ppl

(1,233 - 7,100^SF)

From $1,027/MO

Located just off Interstate 29 in the Gateway Business Park

Simpson Building

102 N Krohn Pl

4 Spaces, 1 ^ppl

(122 - 140^SF)

Located in eastern Sioux Falls, the area surrounding the property is known for its bustling business community. With easy access to I-229 and public transit, the location provides convenience for both employees and clients. Prospective Office / Office Building tenants will appreciate the amenities that the area has to offer, making it an ideal choice for their business needs. Nearby attractions and businesses include the beautiful Falls Park, the lively SculptureWalk, Caribou Coffee, Last Stop CD Shop and Popeyes.

4205 W. 53rd Street

2 Spaces, 1 - 32 ^ppl

(2,715 - 3,977^SF)

From $2,262/MO

Located northwest of the intersection at 57th & Louise Area neighbors include New Beginnings Faith Church, Avera, D'Luxe Suites, Levo Credit Union, USPS South Carrier Annex, Empire Mall, INTEX Cleaning & Restoration Easy access to I-229

1607 North C Avenue

1 Space, 1 - 18 ^ppl

(2,254^SF)

From $2,066/MO

The location, situated at the north end of Sioux Falls off Minnesota Ave in the industrial park, offers availablity to the airport and interstate access for your new office location. Neighboring businesses include Cardinal Health, Daniels-Olsen, Design Tanks, Viaflex and Dey Distributing.

SMP Office Suite 1-3

516 N Garfield Cir, Suite 1-3

1 Space, 1 - 3 ^ppl

(1,100^SF)

Located on a cul-de-sac in a Light Industrial zone but also home to commercial, office and residential. Neighbors are Sioux Merchant Patrol, Casey's, Dreamers Outlet and Life Church

Summit Properties Offices

47392 272nd St, Suite 3-5

1 Space, 1 - 8 ^ppl

(1,000^SF)

South on Highway 115 (Minnesota Ave) out of Sioux Falls, turn west on 272nd Street, building on north side of 272nd Street

Two City Centre

370 West Anchor Dr

1 Space, 1 - 18 ^ppl

(2,250^SF)

Dakota Dunes, SD

600 E. 7th Street, 2nd Floor

1 Space, 1 - 15 ^ppl

(1,901^SF)

Located in downtown Sioux Falls in the historic East Side Fire Station Area neighbors include Heritage Park, Cherapa Place Development, Monk's Ale House, Roots of Brasil, Sioux Area Metro, Johnstone Supply Sioux Falls

1610 N Minnesota Avenue Office

1 Space, 1 - 39 ^ppl

(4,877^SF)

From $7,112/MO

Located on North Minnesota Avenue just south of the Sioux Falls Airport Area neighbors include A&B Business Solutions, Levo Federal Credit Union, US Bank, Kum & Go, Xcel Energy, Bell Incorporated, Sioux Falls Regional Airport Minnesota Avenue Traffic Count: 11,800 vpd

5604 W. 41st Street

1 Space, 1 - 22 ^ppl

(2,700^SF)

From $2,249/MO

Located on 41st Street west of Marion Road Area neighbors include Kappenman Family Dental, Lewis Drug, US Bank, Wells Fargo Bank 41st Street Traffic Count: 17,700 vpd

100 N. Krohn Place

2 Spaces, 1 - 2 ^ppl

(275 - 297^SF)

Located between E. 10th Street and E. 8th Street on N. Krohn Place Area neighbors include Caribou Coffee, Take 5 Oil Change, Taco John's, Boys & Girls Clubs of the Sioux Empire, Children's Home Shelter, Casey's, GreatLIFE

4320 S. Louise Avenue, 200

4320 South Louise Avenue

2 Spaces, 1 - 13 ^ppl

(250 - 300^SF)

Located on Louise Avenue just south of the Empire Mall Area neighbors include Five Guys, Caribou Coffee, The Empire Mall, Popeyes Louisiana Kitchen, Levo Credit Union, Pomegranate Market, Qdoba, GreatLIFE Woodlake Louise Avenue Traffic Counts: 22,100 vpd

Cherapa Place I, 3rd Floor

300 N. Cherapa Place

1 Space, 1 - 79 ^ppl

(9,837^SF)

From $19,263/MO

Located along North Cherapa Place and East 6th Street in downtown Sioux Falls, just steps from the Big Sioux River. The property is within walking distance of local favorites like Rivage Oak Kitchen and Pomegranate Market, and near the growing Steel District.

621 West Russell Street

1 Space, 1 - 161 ^ppl

(20,141^SF)

From $16,783/MO

Located along W Russell Street in Sioux Falls, this commercial property offers excellent visibility and easy access to major thoroughfares. Surrounded by a mix of businesses and just minutes from downtown, it’s a prime spot for office, service, or light industrial use. Russell St. Traffic Count: 25,100 VPD

Bluepeak

5100 S Broadband Lane

2 Spaces, 1 - 96 ^ppl

(5,526 - 7,603^SF)

Located off of west 57th street, this office space neighbors Farm Credit Services of America, SkyZone Trampoline Park, Windsor Mortgage, Bluepeak, and more!

5929 S. Mogen Avenue

2 Spaces, 1 - 115 ^ppl

(3,530 - 14,400^SF)

From $1,470/MO

Located southwest of the I-229/Louise Avenue interchange Area neighbors include Holiday Inn Express & Suites, Five Star Call Centers, Avera Research Institute, Comfort Inn & Suites, Hampton Inn & Suites, Missouri River Energy Services, Avera Heart Hospital, Avera Behavioral Health Center

817 W. Russell Street

2 Spaces, 1 - 42 ^ppl

(1,801 - 5,292^SF)

From $1,801/MO

Located west of downtown, near the airport area and along W. Russell Street. Russell St. Traffic Count: 26,800 VPD

3409 N. Potsdam Avenue

1 Space, 1 - 80 ^ppl

(10,000^SF)

From $8,958/MO

Just off Benson Road with easy access to I-229 Area Neighbors: Circle K, Electric Construction, & Hardscapes Outlet

115 North Main Avenue

1 Space, 1 - 49 ^ppl

(6,138^SF)

From $613,800

Area Neighbors: Pizza Ranch, Subway, Central Valley Golf Course, West Central High School, Dairy Queen, Caribou Coffee

304 W. Highway 38, Suite 114

304 South Dakota 38

1 Space, 1 - 13 ^ppl

(1,646^SF)

From $1,885/MO

Located in the Hartford Professional Center Co-tenants include Reliabank, HyVee Pharmacy, Hartford Dental Clinic, Hartford Spinal Care, Dave & Co Real Estate, Edward Jones SD Highway 38 Traffic Count: 3,707 vpd

409 E 41st St

1 Space, 1 - 2 ^ppl

(288^SF)

Located near Roxi & Co, Polar Bites, Balance Life Massage Therapy, Tranquility Therapeutic Massage & Spa, Insights Rehab Counseling, Molly Maid of Sioux Falls, Recharge, Corner Stone School, Nyberg's ACE Handyman Services, Vanessens Salon & Suites